GSK-963, 98%, 25mg

$499.00
In stock
SKU
Q693

GSK963 is a chiral small-molecule inhibitor of RIP1 kinase (RIPK1) with an IC50 of 29 nM in FP binding assays. It is >10 000-fold selective for RIP1 over 339 other kinases. GSK'963 is significantly more potent than Nec-1 in both biochemical and cellular assays, inhibiting RIP1-dependent cell death with an IC50 of between 1 and 4 nM in human and murine cells.

 

THIS PRODUCT IS NOT FOR HUMAN USE

This Product Is For Research Use Only

Cat#: Q693

Name: GSK-963

CAS#: 2049868-46-2

Chemical Formula: C14H18N2O

Molecular Weight: 230.311

Appearance:White to off-white solid powder

Purity:>98%

 

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