Oclacitinib, 98%, 50mg
Oclacitinib / PF03394197, is a novel Janus kinase inhibitor with activity against cytokines involved in allergy. Oclacitinib inhibited JAK family members by 50% at concentrations (IC50 's) ranging from 10 to 99 nM and did not inhibit a panel of 38 non-JAK kinases (IC50 's > 1000 nm). Oclacitinib was most potent at inhibiting JAK1 (IC50 = 10 nm). Oclacitinib also inhibited the function of JAK1-dependent cytokines involved in allergy and inflammation (IL-2, IL-4, IL-6, and IL-13) as well as pruritus (IL-31) at IC50 's ranging from 36 to 249 nM.
THIS PRODUCT IS NOT FOR HUMAN USE
This Product Is For Research Use Only
Cat#: Q675
Name: Oclacitinib
CAS#: 1208319-26-9
Chemical Formula: C15H23N5O2S
Molecular Weight: 337.44
Appearance: white to off-white solid powder
Purity: >98%
Delivery within 3-7 Days
For Bulk quantities,